According to current engineering operation experiences and the new measurement and control (M&C) requirements for HL-2M tokamak, referring to the ITER control, data acquisition and communication standard, the operation and management of HL-2M M&C are focused on in this paper. Through the configuration and management for all plant systems, high performance networks architecture, physical data storage system design and expansion, operation status monitoring and alarm control system, an integrated system management platform for HL-2M tokamak M&C is created. This study is targeted on the optimization of the experimental signal quality, realization of effective real-time signal transmission, enhancement of automatic management level, and guarantee of equipments and data in the experimental process and with high feasibility.